Histone H4 lysine 16 acetylation controls central carbon metabolism and diet-induced obesity in mice

Noncommunicable diseases (NCDs) account for over 70% of deaths worldwide. Previous work has linked NCDs such as type 2 diabetes

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Progressive Phosphorylation Modulates the Self-Association of a Variably Modified Histone H3 Peptide

Protein phosphorylation is a key regulatory mechanism in eukaryotic cells. In the intrinsically disordered histone tails, phosphorylation is often a

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PRMT2 promotes dextran sulfate sodium-induced colitis by inhibiting SOCS3 via histone H3R8 asymmetric dimethylation

Background and purpose: There is emerging evidence for the critical roles of epigenetic modifiers in the development of inflammatory bowel disease

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Histone H4R3 symmetric di-methylation by Prmt5 protects against cardiac hypertrophy via regulation of Filip1L/β-catenin

Background and purpose: Although histone lysine methylation has been extensively studied for their participation in pathological cardiac hypertrophy, the potential regulatory

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