Histone H4 lysine 16 acetylation controls central carbon metabolism and diet-induced obesity in mice
Noncommunicable diseases (NCDs) account for over 70% of deaths worldwide. Previous work has linked NCDs such as type 2 diabetes
Read moreNoncommunicable diseases (NCDs) account for over 70% of deaths worldwide. Previous work has linked NCDs such as type 2 diabetes
Read moreProtein phosphorylation is a key regulatory mechanism in eukaryotic cells. In the intrinsically disordered histone tails, phosphorylation is often a
Read morePlant homeodomain (PHD) fingers are often present in chromatin-binding proteins and have been shown to bind histone H3 N-terminal tails.
Read moreBackground and purpose: There is emerging evidence for the critical roles of epigenetic modifiers in the development of inflammatory bowel disease
Read moreThe main strategy for preventing porcine reproductive and respiratory syndrome (PRRS) is vaccination. However, current commercial porcine reproductive and respiratory
Read moreBackground and purpose: Although histone lysine methylation has been extensively studied for their participation in pathological cardiac hypertrophy, the potential regulatory
Read moreBackground: Congenital heart defects (CHDs) have multifactorial etiology with the complex interplay of genetic and environmental factors. Environmental impact can have
Read moreBackground: Induction immunosuppressive therapy is used to prevent rejection and maintain allograft function in transplantation. Rabbit antithymocyte globulin (rATG), a T-cell
Read moreBackground: Overweight and obesity are associated with deaths and diseases worldwide. Cordia ecalyculata is a plant marketed as a slimmer. Methods: The
Read moreClinical outcomes in patients with WHO grade II/III astrocytoma, oligodendroglioma or secondary glioblastoma remain poor. Isocitrate dehydrogenase 1 (IDH1) is
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